• Users Online: 130
  • Print this page
  • Email this page
RESEARCH ARTICLE
Year : 2018  |  Volume : 3  |  Issue : 1  |  Page : 15-20

Prognostic impact on Type B acute aortic dissection with renal insufficiency: A single-center study


Department of Cardiology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China

Correspondence Address:
Xiang Ma
Department of Cardiology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011
China
Yi-Tong Ma
Department of Cardiology, The First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011
China
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/cp.cp_6_18

Get Permissions

Aims: The aim was to study the impact of renal insufficiency on type B acute aortic dissection (AAD), in terms of in-hospital mortality and long-term survival. Materials and Methods: A total of 241 consecutive patients with type B AAD from 2007 to 2014 were enrolled. Based on estimated glomerular filtration rate, two groups were formed: Group A, with e-GFR <60 ml/min/1.73 m2 and Group B, with e-GFR ≥60 ml/min/1.73 m2 and were compared. Logistic regression and Cox regression analyses were used to identify predictors of in-hospital mortality, mortality during follow-ups, and long-term survival. Results: There was no significant difference in general characteristics and hemodynamic status between the two groups (P > 0.05). Both groups received main cardiovascular drugs and/or interventional therapies (P > 0.05). Group A had longer coronary care unit stays than Group B (P < 0.05). Multivariate logistic regression model showed white blood cell (WBC) count (odds ratio [OR], 1.107; 95% confidence interval [CI], 1.016–1.206; P < 0.05), e-GFR < 60 ml/min/1.73 m2 (OR, 4.809; 95% CI, 1.716–13.480; P < 0.05), and in-hospital hypotension (OR, 13.87; 95% CI, 2.544–75.591; P < 0.05) as significant predictors for in-hospital mortality. This was also significant in Cox regression analysis: WBC count (Hazard ratio (HR), 1.108; 95% CI, 1.029–1.194, P < 0.05), e-GFR <60 ml/min/1.73 m2 (HR, 2.572; 95% CI, 1.014–6.524; P < 0.05), and in-hospital hypotension (HR, 3.309; 95% CI, 1.133–9.666; P < 0.05). Kaplan–Meier analysis showed Group A having much lower cumulative survival than Group B. Conclusion: This study shows that moderate-to-severe renal insufficiency is an independent predictor of mortality in type B AAD both during hospital stay and on subsequent follow-ups.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed463    
    Printed55    
    Emailed0    
    PDF Downloaded60    
    Comments [Add]    

Recommend this journal