Close
  Indian J Med Microbiol
 

Figure 3: Statins regulate angiogenesis through protein prenylation-regulated PI3K-Akt-eNOS signaling cascade or Cav-1-regulated eNOS activity. HMGCR: HMG CoA reductase. In addition, statins also reduce cell cholesterol levels, which may reduce lipid raft content and Cav-1-eNOS interaction, thereby alleviating the inhibition on eNOS and enhancing its activation

Figure 3: Statins regulate angiogenesis through protein prenylation-regulated PI3K-Akt-eNOS signaling cascade or Cav-1-regulated eNOS activity. HMGCR: HMG CoA reductase. In addition, statins also reduce cell cholesterol levels, which may reduce lipid raft content and Cav-1-eNOS interaction, thereby alleviating the inhibition on eNOS and enhancing its activation